Webcast Information

Optimizing Downstream Purification Processes:
New approaches and benefits to bioprocess chromatography

Increased cell culture titers and product demand is driving higher protein mass loads into downstream processing. These higher titers have created a downstream bottleneck placing an increased emphasis on the purification of biomolecules and the need for new solutions. There is a greater need for process flexibility to maintain column and tank sizes due to facility fit and an escalated challenge for impurity removal with the higher loads.

Join Shelly Cote Parra, Sr. Applications Scientist at Life Technologies, as she discusses new approaches to improve performance of cation exchange and anion exchange chromatography. Potential improvements in bioprocess chromatography include optimal particle size, pore size, and surface chemistry, as well as improved process performance. Capacity and resolution of the purification of biomolecules will be addressed, as will an approach for anion exchange flow-through chromatography.